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Ageing biology, biomarkers, interventions, and research literacy.

Functional Age

Definition

Functional age is an estimate of ageing based on how well a person functions physically, cognitively, and physiologically, rather than only on how many years they have lived. It can include measures such as walking speed, grip strength, balance, mobility, cognition, aerobic capacity, daily activity, and the ability to recover from stressors or illness. [1] [2] [3]

Why It Matters in Ageing Research

Functional age matters because healthspan depends on what people can do, not just on molecular markers or disease labels. Two people with the same chronological age can differ greatly in mobility, strength, independence, resilience, and risk of disability. Researchers and clinicians use functional measures to study frailty, predict adverse outcomes, evaluate interventions, and connect biological ageing research to real-world abilities that affect quality of life. [2] [4] [5]

Common Confusion

Related Reading

References

  1. Kirkwood, T. B. L. (2005). Understanding the odd science of aging. https://pubmed.ncbi.nlm.nih.gov/15784673/
  2. Studenski, S., et al. (2011). Gait speed and survival in older adults. https://pubmed.ncbi.nlm.nih.gov/21205966/
  3. Bohannon, R. W. (2008). Hand-grip dynamometry predicts future outcomes in aging adults. https://pubmed.ncbi.nlm.nih.gov/18790810/
  4. Fried, L. P., et al. (2001). Frailty in older adults: Evidence for a phenotype. https://pubmed.ncbi.nlm.nih.gov/11253156/
  5. Cesari, M., et al. (2009). Biomarkers of aging and physical function. https://pubmed.ncbi.nlm.nih.gov/19414544/
Note

This glossary entry is provided for educational purposes only and does not constitute medical advice.